Press center
Welcome to the Press center. Here’s where we take a closer look at research and development stories, trends and developments shaping the diverse areas in which our customers and partners work.
12 November 2021
Human DNA contamination is still the major bottleneck in microbiology. Fast and efficient human DNA removal opens doors toward more accurate and timely diagnostics of infectious diseases which can help save lives of millions of patients. We prepared comprehensive review with analysis of most used techniques available on the market, compared their efficacy and outlined perspective of human DNA depletion for mNGS application in rapid pathogen detection. You can download and read it now.
Detection of Pathogens in clinical samples via MALDI-TOF MS Technology – Benefits vs Challenges.
26 January 2022
One of the most commonly used methods for microbial identification is 18S and 16S ribosomal RNA sequencing. Currently a new technology, MALDI-TOF MS (matrix-assisted laser desorption ionization-time of flight mass spectrophotometry) has emerged as a potential technique for the diagnosis of microbes in clinical specimens. This technique is very rapid, has high specificity and sensitivity as compared to other conventional methods of pathogen identification. Microbiologists have used this technique not only for diagnostic purposes but also in epidemiological studies, strain identification and typing, detection of toxins, identification of biological warfare agents, water, and foodborne pathogen, detection of antimicrobial resistance, and identification of urinary tract and blood pathogen.
Opportunistic Fungal Infections and how mNGS can Help
19 January 2022
What are opportunistic fungi? Opportunistic fungi are a group of fungi that cause secondary infections in those vulnerable individuals whose immune system is compromised by a pathogen that caused some primary infection. These fungi usually don’t cause diseases in normal healthy individuals and target immunocompromised people only, often causing some serious even life-threatening secondary infections.
DNA barcoding and its use to identify different pathogens
11 January 2022
Identifying pathogens down to the species level is vital for the proper treatment of diseases. However, many pathogens (like several species of fungi and bacteria) are obligate parasites and cannot be cultured in a lab. The ones that can be grown in a lab are hard to identify compared to higher animals because morphological identification of microbes leads to errors. Medically important parasites are also hard to identify using morphological methods.
CRISPR-Cas- An Insight to combat Infectious Diseases and other disorders
30 November 2021
Infectious diseases pose a major threat to public health and result in high morbidity and mortality. There is a need to rapidly diagnose and treat these infections to improve public health. For that purpose, a detailed understanding of interaction and host and pathogen (viruses, bacteria parasites fungi) is required.
How to Save 50%+ of Your Sequencing Cost with PaRTI-Seq®
19 November 2021
Cost of sequencing is the main economic impediment for rapid diagnostics of infectious diseases in clinical microbiology today. Micronbrane developed technology that not only enables faster and more accurate detection of pathogens but also allows to reduce sequencing cost by more than 50%! Check about cost effective technology designed by Micronbrane for diagnostics by mNGS in this infographic article.