PaRTI-Seq Analysis is designed to overcome the computational and interpretive challenges of metagenomic sequencing by turning complex datasets into clear, actionable results. Each sequencing run can generate millions of reads, including microbial genomes, host DNA, and environmental noise. Without carefully curated databases and robust pipelines, even experienced labs can encounter false positives, missed detections, and inefficient sequencing runs.
Metagenomic next-generation sequencing (mNGS) is transforming how laboratories study microbial communities, pathogens, and their interactions with hosts and environments. Unlike culture or targeted assays, it provides a hypothesis-free, comprehensive view of all genetic material in a sample.
We focus exclusively on metagenomics, delivering technologies that reduce contamination, simplify workflows, and increase sensitivity while remaining cost-effective for research, clinical, biopharma, and industrial applications. By enabling analyses that were once slow, incomplete, or impractical, we extend the reach of mNGS across discovery, diagnostics, and development with our PaRTI-Seq™ and PRiSM™ workflows.
mNGS enables direct investigation of infection processes and immune modulation across host tissues and timepoints. Researchers can identify pathogens that evade culture, characterize mixed infections, and correlate microbial presence with immune response.
Metagenomic data generated through Micronbrane workflows reveal pathways linked to virulence, metabolism, and microbial adaptation. These insights support both fundamental discovery and applied microbiology research.
mNGS connects discovery to application by characterizing microbial signatures in experimental models, vaccine development, and biopharma research pipelines.
Micronbrane’s host depletion and ultralow-input library preparation kits capture the full diversity of microbial communities, including rare, low-abundance, and unculturable species across human, animal, and translational studies.
Micronbrane’s platform supports the identification of novel or resistant organisms and the tracking of antimicrobial resistance gene transfer. mNGS enables surveillance of emerging threats and characterization of new resistance mechanisms before they spread widely.
Integrating the Devin Host Depletion Filter into single-cell workflows rebalances sample composition so microbial material falls within the capture range of scRNA-seq and scDNA-seq platforms.
Conventional diagnostics rely on culture or targeted panels that often fail to capture the true range of pathogens. Patients remain undiagnosed when tests return negative or take too long. mNGS provides a single, hypothesis-free assay capable of detecting bacteria, viruses, fungi, and parasites while profiling resistance genes.
Microbiome testing demands methods that can capture the full diversity of organisms, including rare and unculturable species. Culture and PCR often miss low-abundance taxa or overlook functional potential. mNGS delivers a complete picture by sequencing all genetic material in a sample, enabling both taxonomic and functional insights.
Public health teams require rapid and accurate data to detect outbreaks, monitor resistance, and guide interventions. Targeted methods can miss emerging or unexpected threats. mNGS offers unbiased surveillance with strain-level resolution, enabling agencies to track microbial evolution and resistance with precision.
mNGS detects a broad spectrum of potential contaminants, including bacteria, fungi, and mycoplasma, without reliance on culture. This enables early identification of sterility risks in viral vector production and cell expansion workflows, improving process control and patient safety.
Comprehensive metagenomic profiling allows identification of spoilage organisms, foodborne pathogens, and unexpected microbial contaminants. mNGS provides faster and more complete insights than traditional culture, supporting continuous monitoring in manufacturing environments.
mNGS enables simultaneous detection of bacterial, viral, and fungal contaminants across industrial, municipal, and healthcare facilities. By capturing all microbial DNA and RNA in a sample, it supports early warning systems for contamination events and resistant organism spread.
Unbiased sequencing supports rapid identification of infectious agents affecting livestock herds and companion animals. mNGS detects mixed infections and emerging pathogens that may be missed by culture or PCR, supporting veterinary diagnostics and surveillance.
Microbial community shifts can alter yield, performance, or product purity. mNGS characterizes microbial composition and dynamics at any stage of production, supporting root-cause analysis and optimization of fermentation systems.
Conventional assays limit discovery to what is already known. Get high-confidence sequencing results even from low-input or contaminated samples, supporting R&D pipelines and ensuring safety in industrial quality control.
Micronbrane Medical technologies enrich our understanding of microorganisms through innovative metagenomic collection devices, novel host depletion, mNGS-grade reagents, advanced metagenomic sequencing assays, automation instrumentation, plus rapid bioinformatic software.
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