HOW I CAN EXACTLY BENEFIT FROM USING PARTI-SEQ® AND DEVIN® IN MY LAB?

What is your Sequencing Platform

 with using Devinwithout using Devin
Cost per sample
Reagents and consumables   
Sample preparation (per sample) If you don't use sample pre-treatment before microbial DNA extraction, leave this field blank ?
Microbial DNA extraction (per sample) Example: if you have 96 rxns in your kit, input cost for 1 rxns ?
NGS library preparation (per sample)
Example: if you have 96 rxns in your kit, input cost for 1 rxns
?
Sequencing (per run) Include all the cost of reagents for one run of sequencing ?
Labor Data source: Worldpopulationreview, Numbeo and others. See full list here. Default value implies labor of 1 dedicated operator of sequencing instrument ?
 
 
Maintenance (per year) Input according to your Instrument Service Plan. Default annual rate is 8% of full purchasing instrument price. ?
Platform cost
Full purchasing price of platform Instrument Cost according to Illumina Source book, Septemer 2020 ?
Salvage If you don't plan to sell your sequencing instrument, put 0 ?
Depretiation period, years How many years you plan to use your sequencing instrument ?

Cost per sample is % less using Devin filter. Devin filter removes over 95% of leucocytes presenting host DNA contamination in the sample and thus requires 75% less sequencing reads with the same sensitivity. Check how it works here.

How much profit can it generate for hospital/lab (per year)
Annual number of samples Max capacity of the sequencing instrument with standard output requirement 20 million PE150 sequencing reads ?
Price for patient, per test Price per sample ?
Price for patient must not be less than cost per sample
Price for patient must not be less than cost per sample
Cost of stay in hospital Due to earlier diagnosis and thus shorter stay in hospital ?
Price of stay in your hospital per day Source: finder.com analysis of health delivery data from the World Health Organization ?
Average stay in your hospital, days Average cost of stay as a difference for time required for blood culture test (5-6 days) and PaRTI-Seq® (24 hours). ?

All calculations are shown for reference only, doesn’t include overhead and other indirect expenses.

Data sources

  
Full purchasing price of platform. Data source:
https://www.illumina.com/content/dam/illumina-marketing/documents/company/illumina-source-book-september-2020.pdf

Labor. Data sources:
1. https://www.quora.com/What-is-the-average-salary-in-Afghanistan#:~:text=What%20is%20the%20average%20salary%20in%20Afghanistan%3F%20%2D%20Quora.
2. https://bdtravelbook.com/qa/what-is-the-average-salary-in-antigua.html
3. https://www.averagesalarysurvey.com/barbados
4. https://take-profit.org/en/statistics/wages/cuba/#:~:text=What%20is%20average%20wage%20in,by%20National%20Office%20of%20Statistics.
5. https://tradingeconomics.com/cambodia/minimum-wages#:~:text=In%20the%20long%2Dterm%2C%20the,according%20to%20our%20econometric%20models.
6. https://english.enabbaladi.net/archives/2016/05/syrian-employee-salaries/#:~:text=The%20regime%20then%20issued%20an,average%20salary%2025%2C000%20Syrian%20pounds.
7. https://latinoamerica21.com/en/the-reality-of-wages-in-venezuela/#:~:text=According%20to%20the%20OVF%20(Venezuelan,of%20a%20company%20averages%20%24216.
8. https://worldpopulationreview.com/country-rankings/median-income-by-country
9. https://worldpopulationreview.com/country-rankings/average-work-week-by-country
10. https://www.numbeo.com/cost-of-living/prices_by_country.jsp?itemId=105

Price of stay in hosptial. Data sources:
https://www.finder.com/most-expensive-countries-to-be-hospitalized-in

Average stay in your hospital, Data sources:
1. https://data.oecd.org/healthcare/length-of-hospital-stay.htm
2. https://www.hindawi.com/journals/bmri/2018/9438046/

HOW MANY SAMPLES I NEED TO HANDLE TO MAXIMIZE EFFECT OF MY ILLUMINA PLATFORM?

Revenue, Quantity of samples per year

Price of test

Price of test must not be less than cost per sample

Annual number of Samples